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© Neva Press, Inc. 2005

CNS Drug Reviews

Table of Contents

Volume 10, No. 2


89 The Neuropsychopharmacology and Toxicology of 3,4-methyelendioxy-N-ethyl-amphetamine (MDEA)
Roland W. Freudenmann and Manfred Spitzer
[Abstract] [Article] [Single Reprint]
117 Antinociceptive Properties of Fadolmidine (MPV-2426), a Novel a2-Adrenoceptor Agonist
Antti Pertovaara
[Abstract] [Article] [Single Reprint]
127 The Cellular Biochemistry of Cholesterol and Statins:  Insights into the Pathophysiology and Therapy of Alzheimer's Disease
Benjamin Wolozin, James Brown, Catherine Theisler and Simone Silberman
[Abstract] [Article] [Single Reprint]
147   TC-1734:  An Orally Active Neuronal Nicotinic Acetylcholine Receptor Modulator with Antidepressant, Neuroprotective and Long-Lasting Cognitive Effects
Gregory J. Gatto, G. Andrees Bohme, William S. Caldwell, Sharon R. Letchworth, Vincent M. Traina, M. Carmen Obinu, Michel Laville, Michel Reibaud, Laurent Pradier, Geoffrey Dunbar and Merouane Bencherif
[Abstract] [Article] [Single Reprint]
167   ABT-089:  Pharmacological Properties of a Neuronal Nicotinic Acetylcholine Receptor Agonist for the Potential Treatment of Cognitive Disorders
Lynne E. Rueter, David J. Anderson, Clark A. Briggs, Diana L. Donnelly-Roberts, Gary A. Gintant, Murali Gopalakrishnan, Nan-Horng Lin, Mark A. Osinski, Glenn A. Reinhart, Michael J. Buckley, Ruth L. Martin, Jeffrey S. McDermott, Lee C. Preusser, Terese R. Seifert, Zhi Su, Bryan F. Cox, Michael W. Decker and James P. Sullivan
[Abstract] [Article] [Single Reprint]


183   The Biology and Pharmacology of Calcium Channel a2-d Proteins.  Pfizer Satellite Symposium to the 2003 Society for Neuroscience Meeting.  Sheraton New Orleans Hotel, New Orleans, LA.  November 10, 2003.
Chris P. Taylor
[Article] [Single Reprint]
SELECTED ABSTRACTS from the Sixth International Conference on Progress in Alzheimer's and Parkinson's Diseases.  Seville, Spain.  May 8-12, 2003.
191   A Novel Neuroprotective Cholinesterase and Brain-Selective MAO Inhibitor with APP Processing Activity for the Treatment of Dementia Co-Morbid with Depression and Parkinson's Disease
M. H. H. Youdim and Marta Weinstock
[Abstract] [Single Reprint]
192   Effects of Capsule Yi-Zhi on Learning and Memory Disorder and ß-Amyloid Peptide Induced Neurotoxicity in Rats
Xu Jiang-Ping, Wu Hang-Yu, Li Lin and Sun Li Sha
[Abstract] [Single Reprint]
193   The AMPA Receptor Potentiator, LY404187 Modulates Expression of Neurotrophins:  in vitro and in vivo Studies in Cortical and Hippocampal Brain Regions
M. J. O'Neill, M. Mackowiak, V. Lakics, C. A. Hicks, D. Bleakman and P. Skolnick
[Abstract] [Single Reprint]
194   Mapping Cortical and Hippocampal Activation with an AMPA Receptor Potentiator in the Rat Brain Using c-fos Immunocytochemistry and [14C]2-Deoxyglucose Autoradiography
J. H. Fowler, K. Whalley, T. K. Murray, M. J. O'Neill and J. McCulloch
[Abstract] [Single Reprint]
195   Increased Sprouting and Delayed Protection with an AMPA Receptor Potentiator in a Rodent Model of Parkinson's Disease Suggests a Trophic Mechanism of Action
M. J. O'Neill, K. Whalley, C. S. Robinson, M. A. Ward, C. A. Hicks and T. K. Murray
[Abstract] [Single Reprint]
196   Effects of Azaindolizindone Derivatives ZSET845 and ZSET1446 on Acetylcholine Release in the Cortex and Learning Impairments in the Rat
Y. Yamaguchi, M. Takano, K. Saitoh, T. Matsuno and S. Kawashima
[Abstract] [Single Reprint]
197   Activation of M1 Muscarinic Receptor by AF267B Protects Hippocampal Neurons from Amyloid ß Peptide Toxicity by Acting on WNT Signalling
G. G. Farias, A. Fisher and N. C. Inestrosa
[Abstract] [Single Reprint]
198   Non-Competitive Inhibition of Solubilized Human g-Secretase by Pepstatin A Methylester, L-685458, Sulfonamides and Benzodiazepines
Gaochao Tian, Cynthia D. Sobotka-Briner, John Zysk, Xiaodong Liu, Cynthia Birr, Mark A. Sylvester, Phil D. Edwards, Clay W. Scott and Barry D. Greenberg
[Abstract] [Single Reprint]
200   E-SAR-94010 (LipoEsar®):  A Pleiotropic Lipoprotein Compound with Powerful Anti-atheromatous and Lipid Lowering Effects
Ramón Cacabelos, Ana Isabel Vallejo, Valter Lombardi, Lucia Fernández-Novoa and Victor Pichel
[Abstract] [Single Reprint]